About this course

  • Released: 07/28/2015
  • Expires: 07/28/2018

SELENOPROTEIN BIOSYNTHESIS DEFECT CAUSES PROGRESSIVE ENCEPHALOPATHY WITH ELEVATED LACTATE

LEARNING OBJECTIVES:

Upon completion of the article by Anttonen et al, the participant should be able to:

  • Describe early clinical features of selenoprotein biosynthesis dysfunction
  • Discuss the pattern of atrophy seen in patients with selenoprotein biosynthesis dysfunction
  • Discuss the potential pathogenic mechanism of brain atrophy.

CORE COMPETENCIES:

The article by Anttonen et al covers the following core competency:

  • Medical Knowledge
     

ELECTROCLINICAL SPECTRUM OF THE NEURONAL CEROID LIPOFUSCINOSES ASSOCIATED WITH CLN6 MUTATIONS

LEARNING OBJECTIVES:

Upon completion of the article by Canafoglia et al, the participant should be able to:

  • Describe early features of CLN6 mutation-associated neuronal ceroid lipofuscinosis (NCL) for patients with childhood-onset 
  • Describe early features of CLN6 mutation-associated NCL for patients with later-onset 
  • Discuss the neurophysiologic findings typically found in patients with CLN6 mutation-associated NCL

CORE COMPETENCIES:

The article by Canafoglia et al covers the following core competency:

  • Medical Knowledge


AUTHOR DISCLOSURES:

Refer to Information and Author section available in the Tool Bar for each article.
 

THIS PAGE IS REQUIRED READING BEFORE BEGINNING ALL ACCME-ACCREDITED COURSES

ACCREDITATION STATEMENT

The American Academy of Neurology designates that participants will receive 1.5 AMA PRA Category 1 CME credits if both CME courses for the issue are completed. Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Academy of Neurology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

MISSION STATEMENT/PROGRAM OBJECTIVES

After evaluating a specific article published in Neurology, participants in the CME activity should be able to demonstrate an increase in, or affirmation of, their knowledge of clinical medicine. Participants should be able to evaluate the appropriateness of the clinical information as it applies to the provision of patient care.

PARTICIPANTS

This program is designed for physicians who are involved in providing patient care and who wish to advance their current knowledge of clinical medicine.

CREDITS

The American Academy of Neurology designates that participants will receive 1.5 AMA PRA Category 1 CME credits if both CME courses for the issue are completed.

The American Academy of Neurology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians.

DISCLOSURES

Steven Lewis, MD receives a stipend in his editorial capacity for Neurology and as an Associate Editor for Continuum: Lifelong Learning in Neurology; has received royalties for the books Field Guide to the Neurologic Examination and Neurology for the Non-Neurologist; and anticipates receiving royalties for the book Neurologic Disorders due to Systemic Disease. James WM Owens Jr. MD, PhD receives royalties from UpToDate, Waltham, MA; grant support from NIH (PI, K08NS054882); and a stipend in his editorial capacity for Neurology.

COMMERCIAL SUPPORT

This CME program receives no commercial support.

ACCME