Neurology: Volume 85, Number 1, July 7, 2015
About this course
- Released: 07/07/2015
- Expires: 07/07/2018
GADOLINIUM-BASED MRI CHARACTERIZATION OF LEPTOMENINGEAL INFLAMMATION IN MULTIPLE SCLEROSIS
LEARNING OBJECTIVES:
Upon completion of the article by Absinta et al, the participant should be able to:
- Recognize that the processes that underlie the progressive phase of multiple sclerosis (MS) remain unclear
- Discuss the possibility that one potential candidate area where persistent inflammation may result in neurodegeneration in MS is the leptomeninges
- Recognize that a spectrum of leptomeningeal pathology has been observed in biopsies at the time of clinical presentation and postmortem in MS
- Discuss the findings from this study assessing the prevalence, distribution, and clinical and laboratory associations of leptomeningeal enhancement in MS patients
CORE COMPETENCIES:
The article by Absinta et al covers the following core competency:
- Medical Knowledge
SUBJECTIVE COGNITIVE CONCERNS, AMYLOID-β, AND NEURODEGENERATION IN CLINICALLY NORMAL ELDERLY
LEARNING OBJECTIVES:
Upon completion of the article by Amariglio et al, the participant should be able to:
- Recognize there is increasing evidence that self-report of subjective cognitive concerns (SCC) may herald changes in cognitive function not detectable by standardized neuropsychological tests, but may be associated with early biomarker evidence of Alzheimer disease (AD) pathology
- Recognize that it is currently unclear as to whether amyloid-β (Aβ) or biomarkers of neurodegeneration (ND) independently contribute to the likelihood of SCC
- Discuss the findings from this study assessing whether neuroimaging biomarkers of Aβ and ND are associated with greater SCC in clinically normal older individuals
CORE COMPETENCIES:
The article by Amariglio et al covers the following core competency:
- Medical Knowledge
AUTHOR DISCLOSURES:
Refer to Information and Author section available in the Tool Bar for each article.
THIS PAGE IS REQUIRED READING BEFORE BEGINNING ALL ACCME-ACCREDITED COURSES
ACCREDITATION STATEMENT
The American Academy of Neurology designates that participants will receive 1.5 AMA PRA Category 1 CME credits if both CME courses for the issue are completed. Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Academy of Neurology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
MISSION STATEMENT/PROGRAM OBJECTIVES
After evaluating a specific article published in Neurology, participants in the CME activity should be able to demonstrate an increase in, or affirmation of, their knowledge of clinical medicine. Participants should be able to evaluate the appropriateness of the clinical information as it applies to the provision of patient care.
PARTICIPANTS
This program is designed for physicians who are involved in providing patient care and who wish to advance their current knowledge of clinical medicine.
CREDITS
The American Academy of Neurology designates that participants will receive 1.5 AMA PRA Category 1 CME credits if both CME courses for the issue are completed.
The American Academy of Neurology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians.
DISCLOSURES
Steven Lewis, MD receives a stipend in his editorial capacity for Neurology and as an Associate Editor for Continuum: Lifelong Learning in Neurology; has received royalties for the books Field Guide to the Neurologic Examination and Neurology for the Non-Neurologist; and anticipates receiving royalties for the book Neurologic Disorders due to Systemic Disease. James WM Owens Jr. MD, PhD receives royalties from UpToDate, Waltham, MA; grant support from NIH (PI, K08NS054882); and a stipend in his editorial capacity for Neurology.
COMMERCIAL SUPPORT
This CME program receives no commercial support.
